cCRO

Specializing in the synthesis of novel, complex and challenging small molecule compounds to accelerate your new drug discovery programs

Over the last decade, Bellen has been empowering global pharmaceutical companies and biotech innovators to accelerate their new drug discovery process through innovative chemistry solutions. We have successfully delivered tens of thousands of compounds in quantities ranging from milligrams to kilograms that satisfied the needs of our customers for their discovery to vivo efficacy and toxicity stage studies.

We constantly deliver projects on time with quality and quantity and we are recognized by our customers as being enthusiastic, responsive, flexible and cost-effective in providing chemistry solutions. Our team of synthetic and medicinal chemists continue enhance their technical skills and consistently deliver high-quality and value-added chemistry services to accelerate your lead candidates identification and further development.

Key areas of services

Route design and synthesis of focused libraries

Hit to lead chemistry design and synthesis

Lead optimization and preclinical candidate ion

Non-GMP scale-up to support in toxicity and vivo efficacy studies

Synthesis of impurity markers

Preparation of key intermediates

Synthesis of reference compounds

Analytical method development

Selected chemistry experiences at Bellen:

Unnatural amino acids synthesis
Heterocyclic Sulfonyl chloride synthesis
Heterocyclic boronic acid/ester synthesis
Pd/Cu-catalyzed C-N coupling Reactions
Suzuki reaction of sterically-hindered boronic acid/ester with aryl halides.
Ring-closing metathesis of alkenes
1.1.1 propellane chemistry
Asymmetric Hydrogenation
Photoinduced decarboxylative borylation of carboxylic acids
The synthesis of macrocyclic steroids.
5/6-member ring B-containing compounds synthesis
Remote ive C-H functionalization of aryl compounds
Kumada coupling via directed C-O bond activation
Ir-catalyzed C-H Borylation
Synthesis of indoles

Why is Bellen your preferred partner for chemistry CRO services?

Customer focus, attends to every consideration of customers
Experienced technical and project management teams with more than 250 synthetic and medicinal chemists
Over 95% on-time delivery rate for the known targets, and over 90% for unknown targets
Reliable, flexible and transparent with demonstrated problem-solving skills
Diverse customer base: over 1000 customers across start-ups, biotechs, bio-pharmas and global pharmaceutical companies.
A dedicated team experienced in route design and dealing with complex chemistry.
Responsive project management team involved from RFQ stage to final compound delivery
Flexible service mode available: FTE or FFS

Other Services

Chemistry CDMO Service

Catalog Service

Chemistry CRO Service

Specializing in the synthesis of novel, complex and challenging small molecule compounds to accelerate your new drug discovery programs

Key areas of services

Selected chemistry experiences at Bellen:

Why is Bellen your preferred partner for chemistry CRO services?

Other Services