What We Do
The experienced teams at Bellen Chemistry are extremely conscious of developing appropriate clinical phases in a compliant way. The outcome being robust processes, expediting and enhancing your drug development programs.
Our process R&D team has significant experience in developing and scaling up multi-step processes for complex heterocycles, carbohydrates, nucleosides and nucleotides, organometallic compound, peptides etc. We have successfully developed several asymmetric synthesis, Suzuki, Sonagashira, Kumada and Heck coupling, turbo Grignard, classical halogenations, carbonylation, ozonolysis, Buchwald amination, chiral reduction and many others.
We have internally developed standard procedures for efficiently handling sensitive reagents and catalysts.
The team members are well-versed with all process development aspects like route scouting, alternate reagents and catalysts screening, solvent selection, impurity profiling with control strategy, NoR and PaR studies, DoE / QbD, plant simulation studies, cost competitiveness and sustainability. Experiments are carried out in our modern laboratories equipped with parallel synthesisers, catalyst screening autoclaves, double-jacked flask with fully-automated and controlled utilities and data acquisition software.
Simultaneously dedicated team of experts explores and practices our technology platforms like flow chemistry, photo chemistry, enzyme catalysis etc. The process development team at Bellen comprises of highly qualified scientists and skilled chemists, with more than 300 years of collective experience.
Rich experience in handling a wide range of chemistries, sensitive reagents / catalysts and category compounds
On-site technology platforms, for complementing process development
State-of-the-art facilities, tools and techniques for efficient process development
High productivity and efficient development teams
Effective and transparent communication
Phase-appropriate analytical method development by dedicated quality assurance team
Non-GMP and cGMP manufacturing for key intermediates, RSM, and final API
Specializing in the synthesis of complex chemical compounds to accelerate your drug discovery programs
No. 1, Caida 3rd Street
ShunYi District, Beijing 101300, China